Can I use one of those sightseeing buses just for transport between neighborhoods?

Technically yes, but they’re not really designed for transportation—they’re more for hop-on-hop-off style sightseeing. They circle popular spots like Union Square, Golden Gate Bridge, North Beach, and the Wharf, but the loop is slow and they don’t run as frequently as local transit.

If your goal is to actually get somewhere, Muni, Uber, or even a rental bike will be faster. These buses are more for casually exploring the city if you’ve got time and want to stay above ground.